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Quantitative Systems Toxicology Modeling with guest Dr. Paul Watkins

On today’s episode, Dr. Paul Watkins, the Howard Q. Ferguson Distinguished Professor at Eshelman School of Pharmacy, University of North Carolina at Chapel Hill and the Director of the University of North Carolina Institute for Drug Safety Sciences, discusses quantitative systems toxicology (QST) and quantitative systems pharmacology (QSP) modeling, recent examples of their application, and how they might better inform decision-making in the pharma industry. Dr. Watkins recently wrote a Commentary in PSP related to this topic and it is available here.

PSPod
PSPod
Quantitative Systems Toxicology Modeling with guest Dr. Paul Watkins
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Reverse Translation Special Joint Episode

On this special joint episode of ClinPharmPod, the official podcast for Clinical Pharmacology and Therapeutics, and PSPod, the official podcast of CPT: Pharmacometrics and Systems Pharmacology Karthik Venkatakrishnan from Takeda Pharmaceuticals and Associate Editor for Clinical Pharmacology and Therapeutics, Lang Li, from the Ohio State University and Associate Editor for CPT: Pharmacometrics and Systems Pharmacology, and Valentina Shakhnovich from Children’s Mercy Hospital in Kansas City and Associate Editor for Clinical and Translational Science discuss reverse translation, the theme of a joint issue of articles recently published in the ASCPT journal family. They discuss the concept of reverse translation as a means to maximize the value of the ever-growing reservoir of real-world data in order to more effectively drive future research using retrospective analysis. Please visit the full joint virtual issue by clicking here.

ClinPharmPod
ClinPharmPod
Reverse Translation Special Joint Episode
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Stuart MacLeod on Improving Medicine Use for Children

In this episode Dennis Velasco speaks with Stuart MacLeod from the University of British Columbia about efforts to equip pediatric clinical pharmacologists and clinical pharmacists with the necessary skills in relevant research and educational methods to address a shortfall in the human resource pool, particularly in low- and lower-middle-income countries where a majority of children under 14 years of age reside. You can read more in the June 2017 issue of CPT focused on Drugs for Chirldren.

Listen and subscribe for free on iTunes and Google Play

ClinPharmPod
ClinPharmPod
Stuart MacLeod on Improving Medicine Use for Children
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“Thoughtflow” with guests Mike Smith, Justin Wilkins, and Amy Cheung

On today’s episode, Mike Smith from Pfizer, Justin Wilkins from Occams, and Amy Cheung from AstraZeneca discuss “Thoughtflow”, a set of standards compiled by the DDMoRe consortium to help facilitate the capture, storage, and reporting of knowledge in the context of MID3, as well as to support reproducibility.

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PSPod
"Thoughtflow" with guests Mike Smith, Justin Wilkins, and Amy Cheung
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Pharmacometrics for Immuno-oncology with guest Iñaki F. Trocóniz

This episode features Dr. Iñaki F. Trocóniz discussing how pharmacometric techniques can be used to counteract immuno-response suppression by tumor cells. Read his commentary from the January 2017 issue here. Also, please find additional CPT:PSP articles related to this topic in the Immuno-oncology Virtual Issue, which is available here.

Listen and subscribe for free on iTunes

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PSPod
Pharmacometrics for Immuno-oncology with guest Iñaki F. Trocóniz
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